Lesson 05 / Skeletal Muscle Structure

Skeletal Muscle Structure

Zoom in from a whole muscle down to the sarcomere and learn how muscle fiber types differ in speed and endurance.

From muscle to myofibril

A whole skeletal muscle is wrapped in connective tissue and divided into bundles called fascicles, each containing many individual muscle fibers, and each fiber packed with hundreds of thread-like myofibrils that run its full length.

Illustration of the layered structure of skeletal muscle

The layered structure of skeletal muscle

This illustration traces skeletal muscle structure from the whole muscle down through fascicles, individual muscle fibers, and myofibrils.

01 / MUSCLE

Whole muscle

A skeletal muscle is a bundle of fascicles wrapped in a connective tissue sheath called the epimysium.

02 / FASCICLE

Fascicle

Each fascicle is a bundle of individual muscle fibers wrapped in a layer called the perimysium.

03 / FIBER

Muscle fiber

A muscle fiber is a single, long muscle cell containing many nuclei and hundreds of myofibrils.

04 / MYOFIBRIL

Myofibril

Myofibrils are thread-like structures made of repeating sarcomeres, the basic contractile unit of muscle.

Muscle fiber types

Skeletal muscle fibers come in different types: slow-twitch fibers resist fatigue and support endurance activity, while fast-twitch fibers contract quickly and powerfully but tire more rapidly.

Whole muscle
Fascicle
Muscle fiber
Myofibril
Sarcomere

Structure enables the mechanism

Every level of skeletal muscle's structure, from the whole muscle down to the sarcomere, exists to support the sliding filament mechanism covered in the previous lesson.

KEY IDEA

Structure completes the story started in lesson one.

From the whole muscle down to the sarcomere, every level of skeletal muscle structure exists to support the sliding filament mechanism that lets muscles generate force.

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